Effect of lotus seedpod oligomeric procyanidins on AGEs formation in simulated gastrointestinal tract and cytotoxicity in Caco-2 cells

Author:

Wu Qian12345ORCID,Zhao Kuoquan12345,Chen Yuanyuan6789,Ouyang Yu12345,Feng Yingna12345,Li Shuyi1011129ORCID,Zhang Liang13141516ORCID,Feng Nianjie12345

Affiliation:

1. Key Laboratory of Fermentation Engineering (Ministry of Education)

2. Hubei Key Laboratoy of Industrial Microbiology

3. National “111” Center for Cellular Regulation and Molecular Pharmaceutics

4. Hubei Research Center of Food Fermentation Engineering and Technology

5. Hubei University of Technology

6. College of Food Science

7. Southwest University

8. Chongqing

9. China

10. College of Food Science and Engineering

11. Wuhan Polytechnic University

12. Wuhan

13. State Key Laboratory of Tea Plant Biology and Utilization

14. Anhui Agricultural University

15. Hefei

16. P.R. China

Abstract

This study explored the effects of lotus seedpod oligomeric procyanidins (LSOPC) and their main monomer catechin (CC) on the formation of advanced glycation end products (AGEs) and Caco-2 cytotoxicity during gastrointestinal digestion.

Funder

National Natural Science Foundation of China

State Key Laboratory of Tea Plant Biology and Utilization

Hubei University of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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