Synthesis of 2-[2-(<i>tert</i>-butoxycarbonyl)-3-(acyl)guanidino]ethylamine salts for convergent introduction of acyl guanidines-Reference-Cited by-同舟云学术

Synthesis of 2-[2-(tert-butoxycarbonyl)-3-(acyl)guanidino]ethylamine salts for convergent introduction of acyl guanidines

Published:2022 Issue:17 Volume:46 Page:8131-8137
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Boer Gareth E.¹^ORCID,Hickey Shane M.²^ORCID,Elliott Alysha G.³^ORCID,Pfeffer Frederick M.¹^ORCID

Affiliation:

1. School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria, 3216, Australia

2. Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia

3. Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia

Abstract

A series of acylguanidines with pre-installed ethylamino linkers are described that can be incorporated into larger structures through amide coupling.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ01510B

Reference24 articles.

1. Ditopic crown ether–guanidinium ion receptors for the molecular recognition of amino acids and small peptides

2. Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE)

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4. NG-Acylated Imidazolylpropylguanidines as Potent Histamine H4 Receptor Agonists: Selectivity by Variation of the NG-Substituent

5. Guanidine−Acylguanidine Bioisosteric Approach in the Design of Radioligands: Synthesis of a Tritium-Labeled NG-Propionylargininamide ([3H]-UR-MK114) as a Highly Potent and Selective Neuropeptide Y Y1 Receptor Antagonist

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