Flavonoids induce cell death in Leishmania amazonensis: in vitro characterization by flow cytometry and Raman spectroscopy-Reference-Cited by-同舟云学术

Flavonoids induce cell death in Leishmania amazonensis: in vitro characterization by flow cytometry and Raman spectroscopy

Published:2019 Issue:17 Volume:144 Page:5232-5244
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Araújo Morgana V.¹²³⁴⁵,Queiroz Aline C.¹²³⁴⁵^ORCID,Silva João F. M.¹²³⁴⁵,Silva Amanda E.¹²³⁴⁵,Silva João K. S.¹²³⁴⁵,Silva Girliane R.⁶⁷⁸⁹⁵,Silva Elaine C. O.¹⁰¹¹³⁴⁵,Souza Samuel T.¹⁰¹¹³⁴⁵^ORCID,Fonseca Eduardo J. S.¹⁰¹¹³⁴⁵^ORCID,Camara Celso A.⁶⁷⁸⁹⁵^ORCID,Silva Tania M. S.⁶⁷⁸⁹⁵^ORCID,Alexandre-Moreira Magna S.¹²³⁴⁵^ORCID

Affiliation:

1. Laboratory of Pharmacology and Immunity

2. Institute of Biological Sciences and Health

3. Federal University of Alagoas

4. Maceió

5. Brazil

6. Phytochemical Bioprospecting Laboratory

7. Chemistry Department

8. Federal Rural University of Pernambuco

9. Recife

10. Optics and Nanoscopy Group

11. Institute of Physics

Abstract

The present study investigated gossypetin 3,7,8,4′-tetra-O-methyl ether (1) and kaempferol 3,7-di-O-methyl ether (3) which showed significant leishmanicidal activity without toxic effects to host cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C9AN00948E

Reference70 articles.

1. Control of the leishmaniases: report of a meeting of the WHO expert committee on the control of leishmaniases. Control of the leishmaniases: report of a meeting of the WHO expert committee on the control of leishmaniases , ed. Organization WH , World Health Organization , 2010

2. Leishmaniasis Worldwide and Global Estimates of Its Incidence

3. Antiprotozoal Agents: An Overview

4. Immunopathogenic competences ofLeishmania(V.)braziliensisandL.(L.)amazonensisin American cutaneous leishmaniasis

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