A mesofluidic platform integrating on-chip probe ultrasonication for multiple sample pretreatment involving denaturation, reduction, and digestion in protein identification assays by mass spectrometry

Author:

Nunes-Miranda J. D.12345,Núñez Cristina678910,Santos Hugo M.45236,Vale G.678910,Reboiro-Jato Miguel1112131415,Fdez-Riverola Florentino1112131415,Lodeiro Carlos678910,Miró Manuel16171819,Capelo J. L.678910

Affiliation:

1. Department of Genetics and Biotechnology

2. University of Trás-os-Montes and Alto Douro

3. Vila Real, Portugal

4. Institute for Biotechnology and Bioengineering

5. Centre of Genomics and Biotechnology

6. REQUIMTE

7. Departamento de Química

8. Faculdade de Ciencias e Tecnologia

9. FCT

10. Universidade Nova de Lisboa

11. SING Group

12. Informatics Department

13. Higher Technical School of Computer Engineering

14. University of Vigo

15. Ourense, Spain

16. FI-TRACE Group

17. Department of Chemistry

18. University of the Balearic Islands

19. Palma de Mallorca, Spain

Abstract

A novel mesofluidic platform integrating on-chip probe ultrasonication for automated high-throughput shotgun proteomic assays.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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