Globule and fiber formation with elastin-like polypeptides: a balance of coacervation and crosslinking

Author:

Lau Kirklann1ORCID,Reichheld Sean2,Sharpe Simon2,Cerruti Marta1ORCID

Affiliation:

1. Department of Materials Engineering, McGill University, 3610 University Street Wong Building, 2250 Montreal, QC H3A 2B2, Canada

2. Molecular Medicine, Hospital for Sick Children, Peter Gilgan Center for Research and Learning, 686 Bay St., Room 20.9714, Toronto, ON M5G 1X8, Canada

Abstract

The timing of crosslinking relative to coacervation controls elastin droplet morphology and propensity for forming interconnected droplet networks. We explore this relationship with an elastin-like peptide (ELP) and genipin crosslinker model.

Funder

Canada Research Chairs

Canadian Institutes of Health Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Peptide-based coacervates in therapeutic applications;Frontiers in Bioengineering and Biotechnology;2023-01-04

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