Discovery of vascular endothelial growth factor receptor tyrosine kinase inhibitors by quantitative structure–activity relationships, molecular dynamics simulation and free energy calculation-Reference-Cited by-同舟云学术

Discovery of vascular endothelial growth factor receptor tyrosine kinase inhibitors by quantitative structure–activity relationships, molecular dynamics simulation and free energy calculation

Published:2016 Issue:42 Volume:6 Page:35402-35415
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Juan¹²³⁴⁵,Shu Mao¹²³⁴,Wen Xiaorong¹²³⁴,Wang Yuanliang⁵⁶⁷⁸⁹,Wang Yuanqiang¹²³⁴,Hu Yong¹²³⁴,Lin Zhihua¹²³⁴¹⁰

Affiliation:

1. School of Pharmacy and Bioengineering

2. Chongqing University of Technology

3. Chongqing 400054

4. China

5. Key Laboratory of Biorheological Science and Technology (Ministry of Education)

6. Research Center of Bioinspired Material Science and Engineering

7. Bioengineering College

8. Chongqing University

9. Chongqing 400044

10. College of Chemistry and Chemical Engineering

Abstract

Employing the combined strategy to understand the features of KDR–ligands complexes, and provide a basis for rational design of inhibitors.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA03743G

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