Small intestine submucosa decorated 3D printed scaffold accelerated diabetic bone regeneration by ameliorating the microenvironment-Reference-Cited by-同舟云学术

Small intestine submucosa decorated 3D printed scaffold accelerated diabetic bone regeneration by ameliorating the microenvironment

Published:2024 Issue: Volume: Page:
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Tan Jie¹²³,Chen Zecai²,Xu Zhen²,Huang Yafang²,Qin Lei²,Long Yufeng²,Wu Jiayi²,Yang Hantao²,Chen Xuandu²,Yi Weihong²,Hang Ruiqiang⁴^ORCID,Guan Min¹^ORCID,Wang Huaiyu¹^ORCID,Gao Ang¹,Yang Dazhi²

Affiliation:

1. Center for Human Tissues and Organs Degeneration, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China

2. Department of Spine Surgery & Innovative Laboratory of Orthopedics, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, 518052, China

3. Orthopaedic department, Wuhan Fourth Hospital, Wuhan, 430030, China

4. Shanxi Key Laboratory of Biomedical Metal Materials, Taiyuan University of Technology, Taiyuan, 030024, China

Abstract

3D-printed PLGA/hydroxyapatite/icariin scaffolds with small intestine submucosa coating offer immunoregulatory abilities, enhance angiogenesis and osteogenesis, and show promise for treating bone defects in diabetic patients.

Funder

National Key Research and Development Program of China

Basic and Applied Basic Research Foundation of Guangdong Province

Shenzhen Science and Technology Program

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB00772G

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