A 3D hanging spheroid-filter plate for high-throughput drug testing and CAR T cell cytotoxicity assay-Reference-Cited by-同舟云学术

A 3D hanging spheroid-filter plate for high-throughput drug testing and CAR T cell cytotoxicity assay

Published:2024 Issue:2 Volume:149 Page:475-481
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Chen Zhenzhong¹,Han Seokgyu¹,Kim Sein²,Lee Chanyang¹,Sanny Arleen³,Tan Andy Hee-Meng³,Park Sungsu¹²⁴^ORCID

Affiliation:

1. School of Mechanical Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Korea

2. Department of Biomedical Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Korea

3. Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, Centros, Singapore 138668, Republic of Singapore

4. Department of Biophysics, Institute of Quantum Biophysics (IQB), Sungkyunkwan University (SKKU), Suwon, 16419, Korea

Abstract

3D Hanging spheroid-filter plate (3DHS-FP) comprises a 3D hanging dripper (top) and a spheroid filter plate (bottom). It is designed to streamline spheroid formation and the effortless separation of unbound and dead cells from tumor spheroids.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AN/D3AN01904G

Reference31 articles.

1. The tumor microenvironment and its role in promoting tumor growth

2. Tumor microenvironment complexity and therapeutic implications at a glance

3. 3D Tumor Spheroid and Organoid to Model Tumor Microenvironment for Cancer Immunotherapy

4. Spheroid-based 3D Cell Cultures Enable Personalized Therapy Testing and Drug Discovery in Head and Neck Cancer

5. Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reshaping the tumor immune microenvironment to improve CAR-T cell-based cancer immunotherapy;Molecular Cancer;2024-08-26