Strontium and simvastatin dual loaded hydroxyapatite microsphere reinforced poly(ε-caprolactone) scaffolds promote vascularized bone regeneration

Author:

Li Gen1ORCID,Li Yubao1,Zhang Xianhui2,Gao Pengfei2,Xia Xue1,Xiao Shiqi1,Wen Jing1,Guo Tao3,Yang Weihu2ORCID,Li Jidong1

Affiliation:

1. Research Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China

2. Key Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineering, Chongqing University, Chongqing 400044, China

3. Department of Orthopaedics, Guizhou Provincial People's hospital, Guiyang 550002, China

Abstract

The promotion of vascular network formation in the early stages of implantation is considered a prerequisite for successful functional bone regeneration.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

International Science and Technology Center

Guizhou Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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