Precise quantification of microRNAs based on proximity ligation of AuNPs-immobilized DNA probes-Reference-Cited by-同舟云学术

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Precise quantification of microRNAs based on proximity ligation of AuNPs-immobilized DNA probes

Published:2024 Issue:8 Volume:16 Page:1281-1287
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Li Keyu¹^ORCID,Xiao Peng¹,Yuan Ningning¹,Yan Shujuan²,Zhao Pei³,Zuo Guowei¹^ORCID

Affiliation:

1. Key Laboratory of Diagnostic Medicine Designated by the Chinese Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China

2. Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510620, China

3. Department of Laboratory Medicine, Hebei General Hospital, Shijiazhuang 050051, China

Abstract

MiRNAs are critical regulators of target gene expression in many biological processes. In this study, we developed a simple, specific, and sensitive miRNA detection method based on proximity ligation reaction of AuNPs-immobilized DNA probes, which is easy to operate.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D3AY02136J

Reference51 articles.

1. MicroRNA

2. Novel Fluorescence Switch for MicroRNA Imaging in Living Cells Based on DNAzyme Amplification Strategy

3. Introduction—RNA: From Single Molecules to Medicine

4. MicroRNAs—Future Drug Targets?

5. Alterations of the microRNA network cause neurodegenerative disease

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