Y(OTf)3-catalyzed phosphorylation of 2H-chromene hemiacetals with P(O)–H compounds to 2-phosphorylated 2H-chromenes

Author:

Zheng Shi-Lu12345,Zou Yun-Xiang12345,Wen Zhong12345,Lin Jia-Fu12345,Gu Ling-Hui12345,Chen Long12345ORCID

Affiliation:

1. Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province

2. Sichuan Industrial Institute of Antibiotics

3. School of Pharmacy

4. Chengdu University

5. Chengdu 610016

Abstract

A highly efficient dehydrative phosphorylation of 2H-chromene hemiacetals with P(O)–H compounds was reported, which provides 2-phosphorylated 2H-chromenes in rich diversity with up to 98% yield.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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