Cytotoxic constituents and a new hydroxycinnamic acid derivative from Leontodon saxatilis (Asteraceae, Cichorieae)

Author:

Ҫiҫek Serhat Sezai1234ORCID,Willer Johanna1234ORCID,Preziuso Francesca12345,Sönnichsen Frank6274ORCID,Greil Richard89101112,Girreser Ulrich13234,Zidorn Christian1234ORCID,Jöhrer Karin8910

Affiliation:

1. Department of Pharmaceutical Biology

2. Kiel University

3. 24118 Kiel

4. Germany

5. Department of Pharmacy

6. Otto Diels Institute for Organic Chemistry

7. Kiel

8. Tyrolean Cancer Research Institute

9. 6020 Innsbruck

10. Austria

11. Paracelsus Medical University Salzburg

12. Department of Internal Medicine III

13. Department of Pharmaceutical and Medicinal Chemistry

Abstract

Phytochemical investigation of the aerial parts of Leontodon saxatilis yielded six compounds with antimyeloma activity as well as crepidiaside A as a chemophenetic marker and 5-feruloyl-2α-hydroxyquinic acid as a new hydroxycinnamic acid derivative.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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