Enhanced PCO prevention of drug eluting IOLs via endocytosis and autophagy effects of a PAMAM dendrimer

Author:

Qin Chen12345,Liu Sihao12345,Wen Shimin12345,Han Yuemei12345ORCID,Chen Siqi12345,Qie Jiqiao12345,Chen Hao12345,Lin Quankui12345ORCID

Affiliation:

1. School of Ophthalmology & Optometry

2. Eye Hospital

3. Wenzhou Medical University

4. Wenzhou 325027

5. China

Abstract

Enhanced posterior capsular opacification prevention of drug eluting intraocular lens via the endocytosis and autophagy effects of a PAMAM dendrimer.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Zhejiang Xinmiao Talents Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference27 articles.

1. WHO, Visual Impairment and Blindness, Available online: https://www.who.int/en/news-room/fact-sheets/detail/blindness-and-visual-impairment# , accessed 8 October 2019, 2019

2. Cataracts

3. Lens regeneration using endogenous stem cells with gain of visual function

4. Posterior Capsular Opacification

5. β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens

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