Synthesis of N,N-disubstituted 2-aminothiophenes by the cyclization of gem-difluoroalkenes with β-keto thioamides-Reference-Cited by-同舟云学术

Synthesis of N,N-disubstituted 2-aminothiophenes by the cyclization of gem-difluoroalkenes with β-keto thioamides

Published:2017 Issue:11 Volume:15 Page:2436-2442
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Xuxue¹²³⁴⁵,Wu Mingsheng¹²³⁴⁵,Zhang Juan¹²³⁴⁵,Cao Song¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory of Chemical Biology

2. School of Pharmacy

3. East China University of Science and Technology (ECUST)

4. Shanghai 200237

5. China

Abstract

A novel and effective method for the construction of highly functionalized aminothiophenes via the cyclization of gem-difluoroalkenes with β-keto tertiary thioamides is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00368D

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1. Novel drug designing approach for dual inhibitors as anti-inflammatory agents: implication of pyridine template

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4. D-π-A Sensitizers for Dye-Sensitized Solar Cells: Linear vs Branched Oligothiophenes

5. Bright, Red Single-Molecule Emitters: Synthesis and Properties of Environmentally Sensitive Dicyanomethylenedihydrofuran (DCDHF) Fluorophores with Bisaromatic Conjugation

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