Local conformational changes in the 8–17 deoxyribozyme core induced by activating and inactivating divalent metal ions-Reference-Cited by-同舟云学术

Local conformational changes in the 8–17 deoxyribozyme core induced by activating and inactivating divalent metal ions

Published:2017 Issue:41 Volume:15 Page:8802-8809
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Peracchi Alessio¹²³⁴⁵^ORCID,Bonaccio Maria¹²³⁴⁵,Credali Alfredo¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Life Sciences and Environmental Sustainability

3. University of Parma

4. 43124 Parma

5. Italy

Abstract

Placing 2-aminopurine at position 15 of the 8–17 DNAzyme allows the detection of a specific metal-induced conformational change, apparently coupled to the activation of catalysis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02001E

Reference42 articles.

1. Deoxyribozymes: Selection Design and Serendipity in the Development of DNA Catalysts

2. Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes

3. DNA Catalysis: The Chemical Repertoire of DNAzymes

4. Metal Ion Sensors Based on DNAzymes and Related DNA Molecules

5. Metal Ion-Dependent DNAzymes and Their Applications as Biosensors

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