A dinuclear ruthenium(ii) phototherapeutic that targets duplex and quadruplex DNA
Author:
Affiliation:
1. Department of Chemistry
2. University of Sheffield
3. Sheffield
4. UK
5. Materials Science & Engineering
6. Sheffield S1 3JD
Abstract
A previously reported dinuclear DNA imaging probe has been converted into a phototherapeutic through the incorporation of RuII(TAP)2 fragments (TAP = 1,4,5,8-3 tetraazaphenanthrene).
Funder
Engineering and Physical Sciences Research Council
University of Sheffield
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC05084H
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