Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery-Reference-Cited by-同舟云学术

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Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery

Published:2021 Issue:12 Volume:9 Page:4289-4300
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Herrera Marco¹²³⁴⁵^ORCID,Kim Jeonghwan¹²³⁴⁵^ORCID,Eygeris Yulia¹²³⁴⁵^ORCID,Jozic Antony¹²³⁴⁵,Sahay Gaurav¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences

2. College of Pharmacy

3. Robertson Life Sciences Building

4. Oregon State University

5. Portland

Abstract

Galectin8-GFP cytosolic redistribution to bright puncta serve as sensor for LNP escape from endosomal compartments.

Funder

National Heart, Lung, and Blood Institute

National Eye Institute

Cystic Fibrosis Foundation

National Institutes of Health

Oregon Health and Science University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM01947J

Reference48 articles.

1. mRNA-based therapeutics — developing a new class of drugs

2. Advances in the delivery of RNA therapeutics: from concept to clinical reality

3. Design and development of polymers for gene delivery

4. Overcoming cellular barriers for RNA therapeutics

5. Non-viral vectors for gene-based therapy

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