Covalent conjugation of cysteine-engineered scFv to PEGylated magnetic nanoprobes for immunotargeting of breast cancer cells-Reference-Cited by-同舟云学术

Covalent conjugation of cysteine-engineered scFv to PEGylated magnetic nanoprobes for immunotargeting of breast cancer cells

Published:2016 Issue:43 Volume:6 Page:37099-37109
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Alric Christophe¹²³⁴^ORCID,Aubrey Nicolas¹⁵⁶⁴,Allard-Vannier Émilie¹²³⁴,di Tommaso Anne¹⁵⁶⁴,Blondy Thibaut¹²³⁴,Dimier-Poisson Isabelle¹⁵⁶⁴,Chourpa Igor¹²³⁴,Hervé-Aubert Katel¹²³⁴

Affiliation:

1. Université François Rabelais de Tours

2. EA6295 ‘Nanomédicaments et Nanosondes’

3. F 37200 Tours

4. France

5. UMR1282 INRA ‘Infectiologie et Santé Publique’

6. F 37000 Tours

Abstract

Orientation- and site-directed covalent conjugation of cysteine-engineered scFv to PEGylated SPIONs allows antigen recognition while preserving colloidal properties of nanoprobes.

Funder

Ligue Contre le Cancer

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA06076E

Reference53 articles.

1. Breast MRI: guidelines from the European Society of Breast Imaging

2. Chemical Design of Nanoparticle Probes for High‐Performance Magnetic Resonance Imaging

3. Cancer theranostics: the rise of targeted magnetic nanoparticles