Sensitive hydrazine detection and quantification with a fluorescent benzothiadiazole sensor: selective lipid droplets and<i>in vivo</i>imaging-Reference-Cited by-同舟云学术

Sensitive hydrazine detection and quantification with a fluorescent benzothiadiazole sensor: selective lipid droplets andin vivoimaging

Published:2023 Issue:22 Volume:21 Page:4606-4619
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Santos Camila O.¹,Passos Saulo T. A.¹^ORCID,Sorto Jenny E. P.¹^ORCID,Machado Daniel F. S.¹^ORCID,Correa Jose R.¹,da Silva Júnior Eufrânio N.²^ORCID,Rodrigues Marcelo O.¹,Neto Brenno A. D.¹^ORCID

Affiliation:

1. Laboratory of Medicinal and Technological Chemistry, University of Brasília, Institute of Chemistry (IQ-UnB), Campus Universitário Darcy Ribeiro, Brasília, Distrito Federal, 70910-900, Brazil

2. Institute of Exact Sciences, Department of Chemistry Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil

Abstract

A selective hydrazine sensor in solution based on the 2,1,3-benzothiadiazole heterocycle is efficient forin vitroandin vivoanalyses. This sensor generates water as the only byproduct, avoiding generation of toxic compounds and interference duringin vivoapplications.

Funder

Fundação de Apoio à Pesquisa do Distrito Federal

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Empreendimentos Científicos e Tecnológicos

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00007A