An activatable near-infrared fluorescent probe for methylglyoxal imaging in Alzheimer's disease mice
Author:
Affiliation:
1. School of Chemistry and Molecular Engineering
2. East China Normal University
3. Shanghai 200241
4. China
5. CAS Key Laboratory of Receptor Research
6. Shanghai Institute of Materia Medica
7. Chinese Academy of Sciences
8. Shanghai 201203
Abstract
A near-infrared fluorescent probe for MGO imaging in Alzheimer's disease mouse brains was developed.
Funder
National Natural Science Foundation of China
Chinese Academy of Sciences
State Key Laboratory of Drug Research
National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2020/CC/C9CC08265D
Reference20 articles.
1. The Cellular Phase of Alzheimer’s Disease
2. Active glycation in neurofibrillary pathology of Alzheimer disease: Nε-(Carboxymethyl) lysine and hexitol-lysine
3. Glyceraldehyde caused Alzheimer’s disease-like alterations in diagnostic marker levels in SH-SY5Y human neuroblastoma cells
4. Age- and Stage-dependent Accumulation of Advanced Glycation End Products in Intracellular Deposits in Normal and Alzheimer's Disease Brains
5. Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain
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