Fast and facile preparation of PEGylated graphene from graphene oxide by lysosome targeting delivery of photosensitizer to efficiently enhance photodynamic therapy

Author:

Zeng Yiping12345,Yang Zhangyou12345,Luo Shenglin12345,Li Hong12345,Liu Cong12345,Hao Yuhui12345,Liu Jing12345,Wang Weidong678910,Li Rong12345

Affiliation:

1. State Key Laboratory of Trauma Burns and Combined Injury

2. Institute of Combined Injury

3. Chongqing Engineering Research Center for Nanomedicine

4. College of Preventive Medicine

5. Third Military Medical University

6. Department of Radiation Oncology

7. Shanghai Sixth People Hospital

8. Shanghai Jiao Tong University

9. Shanghai 200233

10. China

Abstract

A fast, facile and mass production method was reported to obtain stable and disperse polyethylene glycol (PEG) modified nanographene (NGO-PEG). Branched polyethylenimine (BPEI) was used to modify the NGO-PEG (NGO-PEG-BPEI) for further application.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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