Tea polyphenols alleviate the adverse effects of diabetes on oocyte quality

Author:

Lu Jun1,Zhao Shu-Xian1,Zhang Man-Yu1,Ji Peng-Yuan1,Chao Shuo1,Li Li-Jun1,Yin Shen1,Zhao Lei2,Zhao Hua3,Sun Qing-Yuan4,Ge Zhao-Jia1ORCID

Affiliation:

1. College of Life Sciences, Institute of Reproductive Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao 266109, P. R. China

2. College of Horticulture, Qingdao Agricultural University, Qingdao 266109, P. R. China

3. Reproductive Medicine Center, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou 450003, P. R. China

4. Fertility Preservation Lab and Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou 510317, China

Abstract

Maternal diabetes reduces oocyte quality. The decreased oocyte quality can be alleviated by tea polyphenols in vitro, such as mitochondrial function, meiosis, and DNA damage.

Funder

National Natural Science Foundation of China

Qingdao Agricultural University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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