Recording physiological and pathological cortical activity and exogenous electric fields using graphene microtransistor arrays in vitro

Author:

Cancino-Fuentes Nathalia1ORCID,Manasanch Arnau1ORCID,Covelo Joana1ORCID,Suarez-Perez Alex1,Fernandez Enrique2ORCID,Matsoukis Stratis34ORCID,Guger Christoph3ORCID,Illa Xavi25ORCID,Guimerà-Brunet Anton25ORCID,Sanchez-Vives Maria V.16ORCID

Affiliation:

1. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

2. Instituto de Microelectrónica de Barcelona (IMB-CNM, CSIC), Spain

3. g.tec medical engineering, Schiedlberg, Austria

4. Institute of Computational Perception, Johannes Kepler University, Linz, Austria

5. Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, Instituto de Salud Carlos III, Spain

6. ICREA, Barcelona, Spain

Abstract

Full-band recordings, including infraslow components, were obtained with graphene SGFETs from cerebral cortex slices. First gSGFETs recordings from human tissue in vitro were obtained. gSGFETs were also used to quantify both exogenous and endogenous electric fields.

Funder

Horizon 2020 - Research and Innovation Framework Programme

Graphene Flagship

Generalitat de Catalunya

H2020 Marie Skłodowska-Curie Actions

Ministerio de Ciencia e Innovación

Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina

Instituto de Salud Carlos III

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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