Carrier-free, self-assembled pure drug nanorods composed of 10-hydroxycamptothecin and chlorin e6 for combinatorial chemo-photodynamic antitumor therapy in vivo

Author:

Wen Yan12345,Zhang Wei12345,Gong Ningqiang12345,Wang Yi-Feng12345,Guo Hong-Bo12345,Guo Weisheng12345,Wang Paul C.678910,Liang Xing-Jie12345ORCID

Affiliation:

1. Laboratory of Controllable Nanopharmaceuticals

2. Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety

3. National Center for Nanoscience and Technology of China

4. Beijing

5. P.R. China

6. Laboratory of Molecular Imaging

7. Department of Radiology

8. Howard University

9. Washington

10. USA

Abstract

Carrier-free nanodrug HCPT/Ce6 NRs were prepared through a simple self-assembly approach for chemo-photodynamic combination therapy of tumors in vivo.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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