Stereoselective Pd-catalyzed etherification and asymmetric synthesis of furanomycin and its analogues from a chiral aziridine
Author:
Affiliation:
1. Centre for new Directions in Organic Synthesis
2. Department of Chemistry
3. Hankuk University of Foreign Studies
4. Yongin, Kyunggi-Do
5. Korea
6. Sogang University
7. Seoul 121-742
Abstract
A chiral aziridine was utilized for the synthesis of the anti-bacterial natural amino acidl-(+)-furanomycin, and its analogues including 5′-epi-furanomycin and norfuranomycin.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00375J
Reference52 articles.
1. Synthesis ofL-Furanomycin and Its Analogues via Furoisoxazolines
2. Straightforward Syntheses of Furanomycin Derivatives and their Biological Evaluation
3. A New Antibiotic. Furanomycin, an Isoleucine Antagonist
4. X-Ray crystal structure determination of furanomycin
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