Construction of a stereocomplex between poly(d-lactide) grafted hydroxyapatite and poly(l-lactide): toward a bioactive composite scaffold with enhanced interfacial bonding

Author:

Shuai Cijun12ORCID,Yu Li1,Feng Pei1ORCID,Peng Shuping23ORCID,Pan Hao4,Bai Xinna5

Affiliation:

1. State Key Laboratory of High Performance Complex Manufacturing, College of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China

2. School of Energy and Machinery Engineering, Jiangxi University of Science and Technology, Nanchang 330013, China

3. NHC Key Laboratory of Carcinogenesis, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, School of Basic Medical Science, Central South University, Changsha, 410078, China

4. Department of Periodontics & Oral Mucosal Section, Xiangya Stomatological Hospital, Central South University, Changsha 410013, China

5. Department of Conservative Dentistry & Endodontics, Xiangya Stomatological Hospital & Xiangya School of Stomatology Central South University, Changsha 410013, China

Abstract

Hydroxyapatite (HAP) grafted with poly( d-lactide) (PDLA) was incorporated into poly(l-lactide) (PLLA) to construct a stereocomplex, thus improving the interfacial bonding between PLLA and HAP like a zip-lock structure in a scaffold.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

Key Research and Development Program of Jiangxi Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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