Quinoline based mono- and bis-(thio)carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models-Reference-Cited by-同舟云学术

Quinoline based mono- and bis-(thio)carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models

Published:2016 Issue:106 Volume:6 Page:104763-104781
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Božić Aleksandra¹²³⁴,Marinković Aleksandar¹²³⁴,Bjelogrlić Snežana⁵³⁴^ORCID,Todorović Tamara R.⁶²³⁴,Cvijetić Ilija N.⁷²³⁴,Novaković Irena⁸²³⁴,Muller Christian D.⁹¹⁰¹¹¹²¹³,Filipović Nenad R.¹⁴²³⁴

Affiliation:

1. Faculty of Technology and Metallurgy

2. University of Belgrade

3. Belgrade

4. Serbia

5. National Cancer Research Center of Serbia

6. Faculty of Chemistry

7. Innovation Center of the Faculty of Chemistry

8. Institute of Chemistry, Technology and Metallurgy

9. Institut Pluridisciplinaire Hubert Curien

10. UMR 7178

11. CNRS

12. Université de Strasbourg

13. 67401 Illkirch

14. Faculty of Agriculture

Abstract

Study of antitumor activity of mono- and bis-quinoline based (thio)carbohydrazones on THP-1 and AsPC-1 cancer stem cells, revealed that thiocarbohydrazones had superior pro-apoptotic activity than carbohydrazones with multi-target profile activities.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA23940D

Reference102 articles.

1. Biological Activities of Hydrazone Derivatives

2. A review exploring biological activities of hydrazones

3. Analgesic, Anti-Inflammatory, and Antiplatelet Profile of Hydrazones Containing Synthetic Molecules

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