Depletion of protein thiols and the accumulation of oxidized thioredoxin in Parkinsonism disclosed by a red-emitting and environment-sensitive probe-Reference-Cited by-同舟云学术

Depletion of protein thiols and the accumulation of oxidized thioredoxin in Parkinsonism disclosed by a red-emitting and environment-sensitive probe

Published:2019 Issue:16 Volume:7 Page:2696-2702
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Hu Guodong¹²³⁴⁵^ORCID,Zhang Baoxin¹²³⁴⁵,Zhou Pengcheng¹²³⁴⁵,Hou Yanan¹²³⁴⁵,Jia Huiyi¹²³⁴⁵,Liu Yuxin¹²³⁴⁵,Gan Lu⁶⁷⁸⁴⁵,Zhang Hong⁶⁷⁸⁴⁵^ORCID,Mao Yiheng¹²³⁴⁵,Fang Jianguo¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry

2. College of Chemistry and Chemical Engineering

3. Lanzhou University

4. Lanzhou

5. China

6. Department of Heavy Ion Radiation Medicine

7. Institute of Modern Physics

8. Chinese Academy of Sciences

Abstract

Protein sulfhydryl groups play a vital role in maintaining cellular redox homeostasis and protein functions and have attracted increasing interests for the selective detection of protein thiols over low-molecular-weight thiols (LMWTs).

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

Lanzhou University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TB/C8TB03101K

Reference70 articles.

1. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple