Rationally synthesized coumarin based pyrazolines ameliorate carrageenan induced inflammation through COX-2/pro-inflammatory cytokine inhibition
Author:
Affiliation:
1. Department of Pharmaceutical Chemistry
2. ISF College of Pharmacy
3. Moga-142001
4. India
5. Department of Pharmacology
6. Department of Chemistry
7. Indian Institute of Technology-Ropar-140001
Abstract
In the present work, coumarin based pyrazolines (7a–g) have been synthesized and investigated for their in vitro and in vivo anti-inflammatory potential.
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/MD/C8MD00457A
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