BODIPY phototether enables oligonucleotide cyclization and subsequent deprotection by tissue-transparent red light

Author:

Wohlrábová Lucie12ORCID,Sahlbach Marlen3,Heckel Alexander3ORCID,Slanina Tomáš1ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry, Flemingovo náměstí 542, Prague 160 00, Czech Republic

2. Department of Organic Chemistry, University of Chemistry and Technology Prague, 166 28, Prague 6, Czech Republic

3. Goethe Universität Frankfurt, Max-von-Laue-Strasse 7, Frankfurt am Main 60438, Germany

Abstract

The BODIPY phototether enables cyclization and subsequent linearization of oligonucleotides by tissue-transparent light. This approach enables the control of oligonucleotide hybridization by light.

Funder

Grantová Agentura České Republiky

Publisher

Royal Society of Chemistry (RSC)

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