Next-generation membrane-active glycopeptide antibiotics that also inhibit bacterial cell division-Reference-Cited by-同舟云学术

Next-generation membrane-active glycopeptide antibiotics that also inhibit bacterial cell division

Published:2023 Issue:9 Volume:14 Page:2386-2398
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Sarkar Paramita¹,De Kathakali¹,Modi Malvika²,Dhanda Geetika¹,Priyadarshini Richa²^ORCID,Bandow Julia E.³,Haldar Jayanta¹^ORCID

Affiliation:

1. Antimicrobial Research Laboratory, New Chemistry Unit and School of Advanced Materials, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bengaluru, 560064, Karnataka, India

2. Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri 201314, UP, India

3. Applied Microbiology, Faculty of Biology and Biotechnology, Ruhr University Bochum, Universitätsstraße 150, 44780 Bochum, Germany

Abstract

A new multi-target, multi-effect glycopeptide antibiotic that compromises membrane integrity, delocalizes cell division proteins and inhibits cell division besides inhibiting cell wall biosynthesis in both Gram-positive and Gram-negative bacteria.

Funder

Deutscher Akademischer Austauschdienst

Department of Science and Technology, Ministry of Science and Technology, India

Jawaharlal Nehru Centre for Advanced Scientific Research

Council of Scientific and Industrial Research, India

Shiv Nadar University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC05600C