Copper-mediated oxidative [3 + 2]-annulation of nitroalkenes and pyridinium imines: efficient synthesis of 3-fluoro- and 3-nitro-pyrazolo[1,5-a]pyridines-Reference-Cited by-同舟云学术

Copper-mediated oxidative [3 + 2]-annulation of nitroalkenes and pyridinium imines: efficient synthesis of 3-fluoro- and 3-nitro-pyrazolo[1,5-a]pyridines

Published:2020 Issue:7 Volume:18 Page:1436-1448
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Motornov Vladimir A.¹²³⁴⁵^ORCID,Tabolin Andrey A.¹²³⁴^ORCID,Nelyubina Yulia V.⁶²³⁴^ORCID,Nenajdenko Valentine G.⁷⁸⁹⁴^ORCID,Ioffe Sema L.¹²³⁴^ORCID

Affiliation:

1. N. D. Zelinsky Institute of Organic Chemistry

2. Russian Academy of Sciences

3. Moscow

4. Russia

5. Higher Chemical College

6. A. N. Nesmeyanov Institute of Organoelement Compounds

7. Department of Chemistry

8. M. V. Lomonosov Moscow State University

9. Moscow, 119991

Abstract

Novel 3-fluoro-pyrazolo[1,5-a]pyridines were obtained via copper(ii)-mediated oxidative [3 + 2]-annulation of in situ generated pyridinium imines and fluoronitroalkenes.

Funder

Russian Foundation for Basic Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02668A

Reference82 articles.

1. L. Yet , Bicyclic pyridines containing ring-junction nitrogen , in Privileged structures in drug discovery: medicinal chemistry and synthesis , John Wiley and Sons, Inc , 1st edn, 2018 , ch. 13, pp. 481–535

2. Hepatitis C Replication Inhibitors That Target the Viral NS4B Protein

3. Pyrazolopyridine antiherpetics: SAR of C2′ and C7 amine substituents