Copper-catalyzed arylation of biguanide derivatives via C–N cross-coupling reactions-Reference-Cited by-同舟云学术

Copper-catalyzed arylation of biguanide derivatives via C–N cross-coupling reactions

Published:2015 Issue:47 Volume:13 Page:11432-11437
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Chen¹²³⁴,Huang Bo¹²³⁴,Bao Ai-Qing⁵⁶⁷⁴,Li Xiao¹²³⁴,Guo Shunna¹²³⁴,Zhang Jin-Quan¹²³⁴,Xu Jun-Zhi¹²³⁴,Zhang Rihao¹²³⁴,Cui Dong-Mei⁵⁶⁷⁴

Affiliation:

1. College of Pharmaceutical Sciences

2. Zhejiang University

3. Hangzhou 310058

4. PR China

5. College of Pharmaceutical Science

6. Zhejiang University of Technology

7. Hangzhou 310014

Abstract

We developed an efficient copper-catalyzed cross-coupling reaction of biguanide hydrochloride derivatives with both aryl iodides and bromides under mild conditions.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01258A

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1. Metformin: a new oral biguanide

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3. Short-term effect of buformin, a biguanide, on insulin sensitivity, soluble fraction of tumor necrosis factor receptor and serum lipids in overweight patients with type 2 diabetes mellitus

4. Conformationally-Restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-Chlorophenylbiguanide (mCPBG) and meta-Chlorophenylguanidine (mCPG)

5. Antimicrobial activity of chlorhexidine diacetate and benzalkonium chloride against Pseudomonas aeruginosa and its response to biocide residues

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