A brain tumor-homing tetra-peptide delivers a nano-therapeutic for more effective treatment of a mouse model of glioblastoma

Author:

Kang Rae Hyung1234,Jang Jeong-Eun56784,Huh Eugene910234,Kang Seong Jae56784ORCID,Ahn Dae-Ro56784ORCID,Kang Jae Seung1112131415,Sailor Michael J.16171819ORCID,Yeo Seung Geun2021234,Oh Myung Sook2210234ORCID,Kim Dokyoung123423ORCID,Kim Hyo Young56784

Affiliation:

1. Department of Biomedical Science, Graduate School

2. Kyung Hee University

3. Seoul 02447

4. Republic of Korea

5. Center for Theragnosis

6. Biomedical Research Institute

7. Korea Institute of Science and Technology (KIST)

8. Seoul 02792

9. Department of Medical Science of Meridian

10. Graduate School

11. Laboratory of Vitamin C and Antioxidant Immunology

12. Department of Anatomy and Cell Biology

13. Seoul National University

14. College of Medicine

15. Seoul 03080

16. Department of Chemistry and Biochemistry

17. University of California

18. La Jolla

19. USA

20. Department of Otorhinolaryngology

21. Head & Neck Surgery

22. Department of Life and Nanopharmaceutical Sciences

23. Department of Anatomy and Neurobiology

Abstract

A new glioblastoma (GBM) targeting peptide is developed and successfully demonstrated the delivery of a nano-therapeutic.

Funder

National Institutes of Health

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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