Synthesis and evaluation of antineurotoxicity properties of an amyloid-β peptide targeting ligand containing a triamino acid-Reference-Cited by-同舟云学术

Synthesis and evaluation of antineurotoxicity properties of an amyloid-β peptide targeting ligand containing a triamino acid

Published:2014 Issue:34 Volume:12 Page:6684-6693
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Honcharenko Dmytro¹²³,Bose Partha Pratim¹²³,Maity Jyotirmoy¹²³,Kurudenkandy Firoz Roshan⁴⁵⁶⁷⁸,Juneja Alok¹²³,Flöistrup Erik¹²³,Biverstål Henrik⁶⁷⁸⁹¹⁰,Johansson Jan⁶⁷⁸⁹¹⁰,Nilsson Lennart¹²³,Fisahn André⁴⁵⁶⁷⁸,Strömberg Roger¹²³

Affiliation:

1. Department of Biosciences and Nutrition

2. Karolinska Institutet

3. S-14183 Huddinge, Sweden

4. Neuronal Oscillations Laboratory

5. Division for Neurogeriatrics

6. KI-Alzheimer Disease Research Center

7. Department of Neurobiology

8. Care Sciences and Society

9. Karolinska Institute

10. 14186 Huddinge, Sweden

Abstract

A new triamino acid enables synthesis of an amyloid-β peptide (Aβ) targeting ligand with additional Aβ–ligand interactions that gives protection towards Aβ-induced reduction of gamma oscillations in hippocampal slice preparation.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00959B

Reference46 articles.

1. Leukocyte chemotactic factor 2: A novel renal amyloid protein

2. A primer of amyloid nomenclature

3. Alzheimer's Disease: Genes, Proteins, and Therapy

4. Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

5. A Portrait of Alzheimer Secretases--New Features and Familiar Faces

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