Biguanide–transition metals complexes as potential drug for hyperglycemia treatment

Author:

Villamizar-Delgado Stephanny12345ORCID,Porras-Osorio Laura M.1234,Piñeros Octavio1234,Ellena Javier6789ORCID,Balcazar Norman101112413,Varela-Miranda Ruben E.1234,D'Vries Richard F.1234ORCID

Affiliation:

1. Facultad de Ciencias Básicas

2. Universidad Santiago de Cali

3. Cali

4. Colombia

5. São Carlos Institute of Chemistry

6. São Carlos Institute of Physics

7. University of São Paulo

8. São Carlos

9. Brazil

10. Molecular Genetics Group

11. Universidad de Antioquia

12. Medellin

13. Department of Physiology and Biochemistry

Abstract

Coordination compounds of Cu(ii), Ni(ii), Co(ii), and Zn(ii) with a type of biguanide were obtained and structurally characterized. The new metal-drugs present biological applications as potential drugs for diabetes and metabolic syndrome.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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