Porous microwell scaffolds for 3D culture of pancreatic beta cells to promote cell aggregation and insulin secretion-Reference-Cited by-同舟云学术

Porous microwell scaffolds for 3D culture of pancreatic beta cells to promote cell aggregation and insulin secretion

Published:2024 Issue:5 Volume:5 Page:2019-2026
ISSN:2633-5409
Container-title:Materials Advances
language:en
Short-container-title:Mater. Adv.

Author:

Chen Huajian¹^ORCID,Zeng Tianjiao¹²,Yoshitomi Toru¹^ORCID,Kawazoe Naoki¹,Komatsu Hirotake³,Yang Yingnan⁴,Chen Guoping¹²^ORCID

Affiliation:

1. Research Center for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan

2. Graduate School of Science and Technology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

3. Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute of City of Hope, 1500 E. Duarte Rd., Duarte, CA 91010, USA

4. Graduate School of Life and Environmental Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan

Abstract

Porous microwell scaffolds of biodegradable polymers of gelatin and poly(lactic-co-glycolic acid) (PLGA) were prepared for 3D culture of pancreatic beta cells to promote the formation of cell aggregates and insulin secretion.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MA/D3MA01048A

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