Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage-Reference-Cited by-同舟云学术

Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage

Author:

Zamora Ana¹²³⁴⁵,Denning Catherine A.⁶⁷⁸⁹,Heidary David K.⁶⁷⁸⁹,Wachter Erin⁶⁷⁸⁹,Nease Leona A.⁶⁷⁸⁹,Ruiz José¹²³⁴⁵^ORCID,Glazer Edith C.⁶⁷⁸⁹^ORCID

Affiliation:

1. Departamento de Química Inorgánica and Regional Campus of International Excellence “Campus Mare Nostrum”

2. Universidad de Murcia

3. and Institute for Bio-Health Research of Murcia (IMIB-Arrixaca)

4. E-30071 Murcia

5. Spain

6. Department of Chemistry

7. University of Kentucky

8. Lexington

9. USA

Abstract

A light-activated prodrug delivers both a DNA damaging metal center and a cytochrome P450 inhibitor to prevent drug resistance.

Funder

Fundación Séneca

National Institute of General Medical Sciences

American Cancer Society

Ministerio de Economía y Competitividad

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

Reference62 articles.

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