Copper(ii) complexes with aromatic nitrogen-containing heterocycles as effective inhibitors of quorum sensing activity in Pseudomonas aeruginosa

Author:

Glišić Biljana Đ.12345,Aleksic Ivana6785,Comba Peter9101112,Wadepohl Hubert9101112,Ilic-Tomic Tatjana6785,Nikodinovic-Runic Jasmina6785,Djuran Miloš I.12345

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. University of Kragujevac

4. 34000 Kragujevac

5. Serbia

6. Institute of Molecular Genetics and Genetic Engineering

7. University of Belgrade

8. 11000 Belgrade

9. Anorganisch-Chemisches Institüt and Interdisciplinary Center for Scientific Computing

10. Heidelberg University

11. 69120 Heidelberg

12. Germany

Abstract

Copper(ii) complexes with aromatic nitrogen-containing heterocycles are a new class of quorum sensing inhibitors that attenuate virulence without a pronounced effect on the bacterial growth, thus offering a lower risk for resistance development.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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