Fusion then fission: splitting and reassembly of an artificial fusion-protein nanocage-Reference-Cited by-同舟云学术

Fusion then fission: splitting and reassembly of an artificial fusion-protein nanocage

Published:2024 Issue:34 Volume:60 Page:4605-4608
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Ohara Naoya¹^ORCID,Kawakami Norifumi¹^ORCID,Arai Ryoichi²³^ORCID,Adachi Naruhiko⁴⁵^ORCID,Ikeda Akihito⁴^ORCID,Senda Toshiya⁴^ORCID,Miyamoto Kenji¹^ORCID

Affiliation:

1. Department of Bioscience and Informatics, Faculty of Science and Technology, Keio University, Yokohama, Kanagawa 223-8522, Japan

2. Department of Biomolecular Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, Ueda, Nagano 386-8567, Japan

3. Department of Applied Biology, Faculty of Textile Science and Technology, Shinshu University, Ueda, Nagano 386-8567, Japan

4. Structural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Oho, Tsukuba 305-0801, Japan

5. Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

Abstract

A subunit protein of an artificial protein nanocage TIP60 was split into two fragments, which successfully reassembled in vivo and in vitro.

Funder

Japan Association for Chemical Innovation

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Keio University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC00115J

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