One-dimensional assembly of functional proteins: toward the design of an artificial cellulosome

Author:

Mori Y.12345,Nakazawa H.62785,Gonçalves G. A. L.12345,Tanaka T.9210115,Umetsu M.62785,Kamiya N.12345

Affiliation:

1. Department of Applied Chemistry

2. Graduate School of Engineering

3. Kyushu University

4. Fukuoka 819-0395

5. Japan

6. Department of Biomolecular Engineering

7. Tohoku University

8. Sendai

9. Department of Chemical Science and Engineering

10. Kobe University

11. Kobe 657-8501

Abstract

Monomeric functional proteins, endoglucanase and cellulose-binding modules, were labeled with a designed tetrabiotin ligand unit and assembled to form a one-dimensional protein nanostructure with a topology and modularity similar to those of a natural cellulosome.

Funder

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Industrial and Manufacturing Engineering,Process Chemistry and Technology,Energy Engineering and Power Technology,Biomedical Engineering,Chemical Engineering (miscellaneous),Chemistry (miscellaneous)

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