Design of high-avidity multivalent ligand structures that target cells with high ligand economy-Reference-Cited by-同舟云学术

Design of high-avidity multivalent ligand structures that target cells with high ligand economy

Published:2022 Issue:70 Volume:58 Page:9802-9805
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Fang Qingqing¹,Guo Pan¹,Zeng Yiting¹,Wang Chenru¹,Jiang Tao¹²^ORCID,Jiang Yunbao¹²^ORCID

Affiliation:

1. Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, Xiamen 361005, China

2. Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), Xiamen 361005, China

Abstract

Novel cell-targeting ligand structures are constructed with a spikey core scaffold, where multiple copies of coiled-coil peptide nanorods are conjugated on the surface of a peptide nanosheet.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC03296A

Reference37 articles.

1. Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

2. Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

3. Multivalency as a Chemical Organization and Action Principle

4. Cancer Cell Targeting Using Multiple Aptamers Conjugated on Nanorods

5. In Vitro Imaging and in Vivo Liver Targeting with Carbohydrate Capped Quantum Dots

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1. On-Demand Elongation of Peptide Nanofibrils at Cellular Interfaces to Modulate Cell–Cell Interactions;Nano Letters;2024-08-30

2. Design and synthesis of multivalent drug delivery system with CA IX inhibitors as ligands;Bioorganic & Medicinal Chemistry;2023-10