Thermoresponsive hydrogel for transcatheter arterial chemoembolization of hepatocellular carcinoma

Author:

Zhao Wei1,Xu Jiabin1,You Yuanyuan2,Guo Zhenhu3ORCID,Xiang Yun1,Hao Kenan1,He Xiaofeng1,Zhao Peng2ORCID

Affiliation:

1. Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China

2. NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 510515, Guangzhou, China

3. State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, 100084, Beijing, China

Abstract

A blend hydrogel with thermoresponsive and injectable properties was proposed for the stable dispersion of lipiodol and epirubicin, the hydrogel has been successfully applied in the embolization of the feeding artery for a VX2 tumor model.

Funder

Nanfang Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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