Cobalt and nickel impair DNA metabolism by the oxidative stress independent pathway-Reference-Cited by-同舟云学术

Cobalt and nickel impair DNA metabolism by the oxidative stress independent pathway

Published:2017 Issue:11 Volume:9 Page:1596-1609
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Kumar Vineet¹²³⁴,Mishra Rajesh Kumar¹²³⁴,Kaur Gursharan¹²³⁴,Dutta Dipak¹²³⁴^ORCID

Affiliation:

1. CSIR-Institute of Microbial Technology

2. Sector 39-A

3. Chandigarh 160036

4. India

Abstract

Cobalt and nickel exposure leads to DNA double-strand breaks, decelerating replication fork progression. In parallel, the metal ions inhibit RecBCD function to block SOS-mediated repair of the damaged DNA.

Funder

Science and Engineering Research Board

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MT/C7MT00231A

Reference97 articles.

1. Cobalt proteins

2. Nickel uptake and utilization by microorganisms

3. Nickel Homeostasis and Nickel Regulation: An Overview

4. Microbial nickel proteins

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