Anthocyanins from black peanut skin protect against UV-B induced keratinocyte cell and skin oxidative damage through activating Nrf 2 signaling
Author:
Affiliation:
1. College of Food Science and Technology
2. Huazhong Agricultural University
3. Wuhan
4. China
5. Key Laboratory of Environment Correlative Food Science (Huazhong Agricultural University)
Abstract
Anthocyanins from black peanut skin could improve the UV-B induced skin damage mainly through the MAPK/Nrf2/HO-1- NQO1-GCLC signaling axis.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Hubei Province
Fundamental Research Funds for the Central Universities
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO00706G
Reference47 articles.
1. Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes
2. The ethyl acetate fraction ofSargassum muticumattenuates ultraviolet B radiation-induced apoptotic cell death via regulation of MAPK- and caspase-dependent signaling pathways in human HaCaT keratinocytes
3. Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling
4. NUTRITIONAL PROTECTION AGAINST SKIN DAMAGE FROM SUNLIGHT
5. Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis
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