A step-wise synthetic approach is necessary to access γ-conjugates of folate: folate-conjugated prodigiosenes-Reference-Cited by-同舟云学术

A step-wise synthetic approach is necessary to access γ-conjugates of folate: folate-conjugated prodigiosenes

Published:2019 Issue:25 Volume:9 Page:14078-14092
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Figliola Carlotta¹²³⁴,Marchal Estelle¹²³⁴,Groves Brandon R.¹²³⁴,Thompson Alison¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Dalhousie University

3. Halifax

4. Canada

Abstract

Despite the vast literature that describes reacting folic acid with a pharmacophore, this route is ineffective in providing the correct regioisomer of the resulting conjugate.

Funder

Nova Scotia Health Research Foundation

Canadian Institutes of Health Research

Breast Cancer Society of Canada

QEII Foundation

Beatrice Hunter Cancer Research Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA01435G

Reference69 articles.

1. Chemistry and Biology of Roseophilin and the Prodigiosin Alkaloids: A Survey of the Last 2500 Years

2. The biosynthesis and regulation of bacterial prodiginines

3. Towards an understanding of bacterial metabolites prodigiosin and violacein and their potential for use in commercial sunscreens

4. Dyeing properties of microbial prodiginine from Zooshikella rubidus for silk fabrics

5. Dyeing and antibacterial properties of cotton dyed with prodigiosins nanomicelles produced by microbial fermentation

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