Towards novel tacrine analogues: Pd(dppf)Cl2·CH2Cl2 catalyzed improved synthesis, in silico docking and hepatotoxicity studies-Reference-Cited by-同舟云学术

Towards novel tacrine analogues: Pd(dppf)Cl₂·CH₂Cl₂ catalyzed improved synthesis, in silico docking and hepatotoxicity studies

Published:2022 Issue:35 Volume:12 Page:22476-22491
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Babu Aravinda¹,Joy Muthipeedika Nibin²,Sunil K.¹^ORCID,Sajith Ayyiliath Meleveetil¹,Santra Sougata²^ORCID,Zyryanov Grigory V.²³,Konovalova Olga A.²,Butorin Ilya I.²,Muniraju Keesaram⁴

Affiliation:

1. Department of Chemistry, SSIT, Sri Siddhartha Academy of Higher Education, Tumkur, Karnataka, India-572107

2. Institute of Chemical Technology, Ural Federal University, 19 Mira Street, Yekaterinburg, Russia-620002

3. I. Ya. Postovskiy Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences, 22 S. Kovalevskoy Street, Yekaterinburg, Russia-620219

4. Government Degree College-Puttur (Affiliated to S. V. University, Tirupati), Narayanavanam Road, Puttur, Chittoor (Dt), Andhra Pradesh, India-517583

Abstract

24 synthesized compounds by various cross-coupling reactions on 6-bromo tacrine. Molecular docking and toxicity prediction studies were also performed.

Funder

Ministry of Science and Higher Education of the Russian Federation

Russian Science Foundation

Council on grants of the President of the Russian Federation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA03225B

Reference24 articles.

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