Interrogation of drug effects on HeLa cells by exploiting new AFM mechanical biomarkers

Author:

Yun Xiaoling12345,Tang Mingjie56784,Yang Zhongbo56784,Wilksch Jonathan J.9101112,Xiu Peng131415164,Gao Haiyang123417,Zhang Feng1234,Wang Huabin56784ORCID

Affiliation:

1. School of Life Science

2. Inner Mongolia Agricultural University

3. Hohhot 010018

4. China

5. Chongqing Key Laboratory of Multi-Scale Manufacturing Technology

6. Chongqing Institute of Green and Intelligent Technology

7. Chinese Academy of Sciences

8. Chongqing 400714

9. Department of Microbiology and Immunology

10. University of Melbourne

11. Parkville

12. Australia

13. Department of Engineering Mechanics

14. Soft Matter Research Center

15. Zhejiang University

16. Hangzhou 310027

17. Department of Biomedical Engineering

Abstract

New AFM mechanical biomarkers including cell brush length, adhesion work and the factor of viscosity are discovered for drug assays.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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