Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications-Reference-Cited by-同舟云学术

Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications

Published:2023 Issue:51 Volume:13 Page:36484-36492
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Qian Mingxing¹,Xu Yuanjian¹,Covey Douglas F.¹²³⁴^ORCID

Affiliation:

1. Department of Developmental Biology, Washington University in St. Louis, 660 S. Euclid Ave., St. Louis, MO, 63110, USA

2. Department of Anesthesiology, Washington University in St. Louis, 660 S. Euclid Ave., St. Louis, MO, 63110, USA

3. Department of Psychiatry, Washington University in St. Louis, 660 S. Euclid Ave., St. Louis, MO, 63110, USA

4. Taylor Family Institute for Innovative Psychiatric Research, Washington University in St. Louis, 660 S. Euclid Ave., St. Louis, MO, 63110, USA

Abstract

Click photolabeling reagents and presursors for chemical biology applications.

Funder

National Institute of Mental Health

Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine in St. Louis

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA07260F

Reference10 articles.

1. Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

2. Labeling Preferences of Diazirines with Protein Biomolecules

3. Multiple functional neurosteroid binding sites on GABAA receptors

4. Validation of Trifluoromethylphenyl Diazirine Cholesterol Analogues As Cholesterol Mimetics and Photolabeling Reagents

5. Design and synthesis of an all-in-one 3-(1,1-difluoroprop-2-ynyl)-3H-diazirin-3-yl functional group for photo-affinity labeling