Triazolopyridopyrimidines: an emerging family of effective DNA photocleavers. DNA binding. Antileishmanial activity-Reference-Cited by-同舟云学术

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Triazolopyridopyrimidines: an emerging family of effective DNA photocleavers. DNA binding. Antileishmanial activity

Published:2015 Issue:17 Volume:13 Page:4903-4917
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Adam Rosa¹²³⁴⁵,Bilbao-Ramos Pablo⁶⁷⁸⁵,Abarca Belén¹²³⁴⁵,Ballesteros Rafael¹²³⁴⁵,González-Rosende M. Eugenia⁹¹⁰¹¹⁵,Dea-Ayuela M. Auxiliadora⁶⁷⁸⁵⁹,Estevan Francisco¹²¹³³⁴⁵,Alzuet-Piña Gloria¹²²³⁴⁵

Affiliation:

1. Departament de Química Orgànica

2. Facultat de Farmàcia

3. Universitat de València

4. 46100 Burjassot

5. Spain

6. Departamento de Parasitología

7. Universidad Complutense de Madrid

8. 28040 Madrid

9. Departamento de Farmacia

10. Universidad CEU Cardenal Herrera

11. 46113 Moncada

12. Departament de Química Inorgànica

13. Facultat de Química

Abstract

Triazolopyridopyrimidine compounds behave as DNA photocleavers through both type I and type II mechanisms.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00280J

Reference63 articles.

1. Guanidiniocarbonyl-pyrrole-aryl conjugates as nucleic acid sensors: switch of binding mode and spectroscopic responses by introducing additional binding sites into the linker

2. Oxidative Nucleobase Modifications Leading to Strand Scission

3. Oxidative Strand Scission of Nucleic Acids: Routes Initiated by Hydrogen Abstraction from the Sugar Moiety

4. Chemical nucleases

5. Artificial metallonucleases

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